Intheswamp
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Member since September 2015
Posts: 1,910
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Post by Intheswamp on Apr 16, 2016 8:11:49 GMT -5
A recent study has been reported that the use of PPI (proton pump inhibitors) such as Prilosec, Nexium, Aciphex, etc., for reducing indigestion/reflux appears to link this medication to *possible* later kidney disease/failure. I've taken Prilosec OTC for several years and instantly stopped taking it upon reading the report of this. Having a brother who was a kidney transplant patient (and had the disease for 35 years) and a mother who spent the last five years of her life on hemo tends to make you pay attention to things like this. PPI and Kidney DiseaseAnyhow, it appears that histamine H2 receptor blockers don't have this issue (might have others, though?) so I'm planning on going that route after I let my system rest for a week or so. I'm curious as to which ones of these work good. Mayo Clinic offers the list below. I'm including the "US Brand Names" in the poll but not the Canadian (figured I'd list them for info/discussion). So if you use a histamine H2 receptor blocker please vote in the poll. Also, a comment about what you use and the severity of your condition. Thanks! US Brand NamesAxid Axid AR Axid Pulvules Heartburn Relief Pepcid Pepcid AC Tagamet Tagamet HB Zantac Zantac 150 Zantac 150 Efferdose Zantac 25 Canadian Brand NamesAlti-Ranitidine Apo-Cimetidine Apo-Famotidine Famotidine
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Post by rockjunquie on Apr 16, 2016 9:17:20 GMT -5
I have to take Prilosec (the knock off) to protect my stomach from the systemic nsaids I have to take. Don't like taking either, so I switched my anti inflammatory to bio available tumeric (curcumin) and got off the stomach stuff. Seems to be working as well for me. I have psoriatic arthritis and psoriasis.
edit to add that I didn't know about the kidney issue. Makes me even happier to be off it.
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chassroc
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Rocks are abundant when you have rocktumblinghobby pals
Member since January 2005
Posts: 3,586
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Post by chassroc on Apr 16, 2016 9:37:50 GMT -5
I have taken prilosec, nexium, zantec, pepcid . Mostly prilosec and zantec and find them to be much more effective than Tums. I read the same articles a couple of months ago and only use zantac and tums. Some years ago I was taking both prilosec and zantac (for a conddition that required surgery). But now I take only on demand which is just a couple of times a year and I doubt it really matters what I take.
I have been very cautious about taking anything that requires long term meds. We always find out later about the "unknown" or "suddenly revealed" side effects. When arthritis started to become a problem years ago I rejoiced when Vioxx and celebrex were discoveredand I took every day until the heart issues side effects became widely known. Sidenote, I still take advil for occasional pain, so how safe is that.
I took lipitor to lower cholesterol for a while but decided that was too risky to take that long term. And I wonder if just lowering the number is important? Lots of people take medication for high blood pressure. I know people who take more than one daily. I wonder how smart that is. On my wife's Mothers side, all the women live to be about 100 and they all have high blood pressure. Her Grandmother loved the fat on meats like prok chops and ate it all the time. So does lowering high blood pressure matter for everyone or only certain people? ( and do they rig the clinical trials to especially accept people like the females in my wife's family who can live to a ripe old age even with the condition?
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Post by rockjunquie on Apr 16, 2016 9:46:26 GMT -5
I have taken prilosec, nexium, zantec, pepcid . Mostly prilosec and zantec and find them to be much more effective than Tums. I read the same articles a couple of months ago and only use zantac and tums. Some years ago I was taking both prilosec and zantac (for a conddition that required surgery). But now I take only on demand which is just a couple of times a year and I doubt it really matters what I take. I have been very cautious about taking anything that requires long term meds. We always find out later about the "unknown" or "suddenly revealed" side effects. When arthritis started to become a problem years ago I rejoiced when Vioxx and celebrex were discoveredand I took every day until the heart issues side effects became widely known. Sidenote, I still take advil for occasional pain, so how safe is that. I took lipitor to lower cholesterol for a while but decided that was too risky to take that long term. And I wonder if just lowering the number is important? Lots of people take medication for high blood pressure. I know people who take more than one daily. I wonder how smart that is. On my wife's Mothers side, all the women live to be about 100 and they all have high blood pressure. Her Grandmother loved the fat on meats like prok chops and ate it all the time. So does lowering high blood pressure matter for everyone or only certain people? ( and do they rig the clinical trials to especially accept people like the females in my wife's family who can live to a ripe old age even with the condition? Charlie, I wonder the same things. I have familial high blood pressure and high cholesterol- my body produces too much. I asked my doctor if high cholesterol was really an issue for some people and he said that "they" just don't know what is normal for some and not others. I agreed to go on crestor (the supposed best of them) if he could prove that I needed it. I had an ultrasound on my neck. It was fine. But, at the same time, my dad's brain literally blew up. I take crestor now. I had heart issues with naprosyn. I was taking 1000 mg a day. (prescribed) It gave me bad heart palpitations. I have tried every nsaid since and have not found one that I am comfortable taking. I don't think the medical community knows everything.
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Deleted
Deleted Member
Member since January 1970
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Post by Deleted on Apr 16, 2016 9:56:47 GMT -5
I don't think the medical community knows everything. Stop thinking and own that concept. A close friend (no it aint me) has bona fide "low T". Dr had him on 4 meds. Then low T was discovered. Testosterone therapy eliminated all four drugs. From hundreds of dollars a month to $30. Insurance won't cover it! I don't understand. vegasjames has a ton of knowledge regarding medical treatment. Wouldn't be surprised if your psoriasis isn't bacterial or viral and indeed could be eliminated. It seems rheumatoid arthritis is just that, bacterial. This thread reminds me how lucky I am. Sorry I had nothing to add about the original topic.
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Post by rockjunquie on Apr 16, 2016 10:04:18 GMT -5
I was hoping vegasjames might find this. I am wondering what he thinks of the curcumin. I'm glad that I switched. I feel a lot better on the whole. And, I eliminated 2 meds.
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Intheswamp
Cave Dweller
Member since September 2015
Posts: 1,910
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Post by Intheswamp on Apr 16, 2016 10:37:05 GMT -5
Good replies, even yours Scott. rockjunquie, my wife picked up some tumeric/curcumin the other day. After she got it I did a little reading on it. It appears that it needs to be used along with Piperine so that the body can use it in the extremities for joint/muscle aches. Does what you're using have Piperine in it...I'm thinking so since you mention that it's "bio available". Thanks for the good report on Curcumin!!! chassroc, it's good that you can take the meds on demand now, I may have to go that route. My problem was reflux at night...to the point I began to worry about esophageal erosion/cancer (I was probably over reacting, but...). Yes, long term use of a medicine can hurt you as much as it helps. But in some situations/conditions there is no alternative and "we do what we gotta do". I've been on generic Lipitor (atorvastatin) for the last year and a half due to LBBB. It has kept my cholesterol numbers down nicely, which I need to keep down. But, I'm thinking that some strange "pains" that I've been getting in my arms and legs are due to the statin...hurts at times enough to wake me in the middle of the night. As for people living to be old while having high blood pressure (and other "ailments") I had an old friend that smoked all of his life...he lived to be in his early 90's....I guess those cigarettes killed him. Naturally, there was a bit of sarcasm in that as it's a fact that cigarette smoking lowers most people's life expectancy and/or quality. Some people smoke all of their lives, live to be old, and never appear to be adversely affected by the smoke BUT they are the exceptions...there are exceptions to most anything so I'm sure there's people who are not seriously affected by high blood pressure. I agree that the medical profession doesn't know everything. Today, it is a good chance that if you or your family isn't proactive in pursuing truth in a loved ones diagnosis and treatment then you or your family may sadly find yourself soon making an appointment with a funeral director.
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Post by rockjunquie on Apr 16, 2016 10:39:50 GMT -5
If you are taking a statin, you should be taking CoQ10. And, yes, my curcumin has pepperine. It is the best one that I could find.
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Intheswamp
Cave Dweller
Member since September 2015
Posts: 1,910
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Post by Intheswamp on Apr 16, 2016 10:58:17 GMT -5
Yes, I'm taking CoQ10, but not sure if a good version or not...seems all the supplement/vitamin/mineral/whatever vendors state that there's is "the best".
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jamesp
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Member since October 2012
Posts: 36,155
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Post by jamesp on Apr 16, 2016 12:37:09 GMT -5
Interesting thread. No simple path.
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Post by vegasjames on Apr 16, 2016 14:45:53 GMT -5
A recent study has been reported that the use of PPI (proton pump inhibitors) such as Prilosec, Nexium, Aciphex, etc., for reducing indigestion/reflux appears to link this medication to *possible* later kidney disease/failure. I've taken Prilosec OTC for several years and instantly stopped taking it upon reading the report of this. Having a brother who was a kidney transplant patient (and had the disease for 35 years) and a mother who spent the last five years of her life on hemo tends to make you pay attention to things like this. Proton pump inhibitors can lead to a lot more than kidney disease. They can also increase the risk of numerous diseases and disorders. Part of this is due to the fact that one role of stomach acid is to protect us from ingested pathogens. Therefore, inhibiting stomach acid increases pathogen infection, including from cancer pathogens. The second problem is that stomach acid is also required for the proper breakdown of proteins since it activates the digestive enzyme pepsin and also for nutrient absorption. Food allergies can result from the absorption of partially digested protein solutes if intestinal inflammation is also present. The vitamins B6, B12 and folate are also acid dependent for absorption from the gut. Inhibited absorption of these vitamins due to a lack of stomach acid leads to a decreased level of a process known as methylation, which is essential for about 4,000 processes in the body. Decreased methylation significantly increases the risk of cancer, heart disease, immune suppression, allergies, infection, hormone imbalances, neurotransmitter disorders, etc.
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Post by vegasjames on Apr 16, 2016 15:22:40 GMT -5
I have taken prilosec, nexium, zantec, pepcid . Mostly prilosec and zantec and find them to be much more effective than Tums. I read the same articles a couple of months ago and only use zantac and tums. Some years ago I was taking both prilosec and zantac (for a conddition that required surgery). But now I take only on demand which is just a couple of times a year and I doubt it really matters what I take. I have been very cautious about taking anything that requires long term meds. We always find out later about the "unknown" or "suddenly revealed" side effects. When arthritis started to become a problem years ago I rejoiced when Vioxx and celebrex were discoveredand I took every day until the heart issues side effects became widely known. Sidenote, I still take advil for occasional pain, so how safe is that. I took lipitor to lower cholesterol for a while but decided that was too risky to take that long term. And I wonder if just lowering the number is important? Lots of people take medication for high blood pressure. I know people who take more than one daily. I wonder how smart that is. On my wife's Mothers side, all the women live to be about 100 and they all have high blood pressure. Her Grandmother loved the fat on meats like prok chops and ate it all the time. So does lowering high blood pressure matter for everyone or only certain people? ( and do they rig the clinical trials to especially accept people like the females in my wife's family who can live to a ripe old age even with the condition? The heart issues with nonsteroidal anti-inflammatory drugs (NSAIDs) including Vioxx (naproxen) and Celebrex (celecoxib) have been known since the day they were put on the market. They just did not tell the public. It is up to the drug companies to report adverse effects to the FDA. The FDA does not test drugs for side effects. So the drug companies routinely hide known side effects from the public until enough deaths or damage occur that they can no longer hide the fact and then thy admit to the side effect. The FDA gives them a million dollar fine and there may be a few lawsuits settled for a few more million but the drug companies have already made billions of dollars off the drug so still come out way ahead. Look at Premarin for example, which took over 30 years for the drug companies to finally admit led to cancer when this fact was being widely reported for decades before that. In order to know that NSAIDs, including ibuprofen (Advil, Motrin, Nuprin, etc) increase the risk of heart attack and stroke all they have to do is to know how these drugs work, which they do. In short NSAIDs work by inhibiting prostaglandins. There are different types of prostaglandins, but the ones targeted are inflammatory prostaglandins. Inflammation is an absolutely essential process to healing since the process involves the increase of blood flow to the injured area from dilation of blood vessels by the prostaglandins. This increases oxygen, nutrients and immune cells to the area to help with the healing process. Over dilation of the blood vessels though make them permeable and they leak fluid in to the surrounding tissue leading to swelling and pain. Therefore, the NSAIDs work by constricting the blood vessels so they do not leak. The decreased blood flow inhibits the healing process though and can increase the risk of organ and tissue damage from a lack of blood flow. For example, during clinical trials there were 2 dozen deaths from ibuprofen induced hepatitis from the ibuprofen cutting off the blood supply to the livers of these test participants. I also know 4 people who had kidney failure after taking a single recommend dose of ibuprofen because the drug shut off the blood supply to the kidneys. This is also a well known, but rarely mentioned side effect of NSAIDs. And as I pointed out these and other side effects due to vascular inhibition (heart attack, stroke, tinnitus, loss of vision, etc.) DO NOT require an overdose or long term use. These can happen with a single recommended dose. Of course this does not occur in all individuals taking these drugs. The people at highest risk are those that already have poor perfusion to the tissues such as those with diabetes, congestive heart failure, or Raynaud's syndrome or Raynaud's disease. Other side effects of NSAIDs can include high blood pressure from the blood vessel constriction, peptic ulcers from inhibition of the stomach lining production and depression. As for high blood pressure there are so many different causes of high blood pressure. Calcium is the number one cause, which is why calcium channel blockers are the most widely prescribed drug for high blood pressure. Then there are medications such as NSAIDs and steroids, epinephrine, angiotensin converting enzyme (ACE), elevated insulin in insulin resistance or the early stages of type 2 diabetes in particular, sodium sensitivity or lack of potassium and low magnesium. Therefore, it is not a problem for everyone and is not always going to occur with aging. As for rigging trials, yes in a way. The numbers were lowered not too long ago to what is considered normal. This way more people can be diagnosed with high blood pressure and they can sell more drugs to treat it. This also brings up a major pet peeve of mine. I detest doctors who will prescribe high blood pressure medication based on one high reading. Same goes for cholesterol medications. Both of these fluctuate greatly throughout the day and multiple readings need to be done to get an average before any treatment. This is especially true in cases of high blood pressure where home readings need to be taken in to account since some people suffer from "white coat syndrome" causing their blood pressure to go up from anxiety when they go to the doctor. Also keep in mind that coffee raises both blood pressure and cholesterol levels due to the caffeine. When people are going in to the doctor for a fasting blood test they are told not to ingest anything other than they can have water or coffee. Yet the coffee can throw off various lab tests including cholesterol, blood sugar and inflammatory markers. I will have to see if I can find the story I posted about my friend who had a stroke because her doctor gave her too high of a dose of Lisinopril for her high blood pressure from white coat syndrome. Too long of a story to retype.
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Post by vegasjames on Apr 16, 2016 16:24:12 GMT -5
I have to take Prilosec (the knock off) to protect my stomach from the systemic nsaids I have to take. Don't like taking either, so I switched my anti inflammatory to bio available tumeric (curcumin) and got off the stomach stuff. Seems to be working as well for me. I have psoriatic arthritis and psoriasis. edit to add that I didn't know about the kidney issue. Makes me even happier to be off it. The stomach issue with NSAIDs are peptic ulcers that can occur and can lead to death from internal bleeding of the ulcers. In fact the FDA estimates that over 16,500 people a year die from the use of NSAIDs, which the vast majority are due to the bleeding ulcers. Personally I think their estimate is way too low since many of the deaths will not be attributed to the drugs. For example, an NSAID induced heart attack or stroke will be listed as death simply from heart attack or stroke with no mention of the NSAID role. And death from an NSAID induced hepatitis will likely be attributed to a viral hepatitis due to the extremely high inaccuracy rate of the antibody tests used to "diagnose" some forms of hepatitis. The false positive rates of antibody tests for things like hepatitis and HIV are EXTREMELY high. Anyway, the reason for the ulcer formation is that there are hormones known as prostaglandins that serve various purposes. One of the prostaglandins is used to produce the protective lining of the stomach. When the NSAIDs interfere with this prostaglandin the stomach acid can directly attack the stomach wall leading to damage and eventual ulceration. Psoriasis is the result of an imbalance of two chemical messengers known as cyclic guanosine monophosphate (cGMP) and cyclic adenosine monophosphate (cAMP). Normally cAMP is dominant. in psoriasis the cGMP becomes dominant instead, and the increased level of cGMP leads to the cellular proliferation seen in psoriasis. Here is my write up on psoriasis that will give you some suggestions: medcapsules.com/forum/showthread.php?tid=2910Building up the adrenals not only helps with the autoimmune component but will also help with the arthritis. Arthritis literally means inflammation of the joint. Our adrenal glands produce the body's anti-inflammatory corticosteroids. Therefore, one of the primary reasons for increased inflammation in the body ins adrenal dysfunction.
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Post by vegasjames on Apr 16, 2016 17:06:52 GMT -5
I have taken prilosec, nexium, zantec, pepcid . Mostly prilosec and zantec and find them to be much more effective than Tums. I read the same articles a couple of months ago and only use zantac and tums. Some years ago I was taking both prilosec and zantac (for a conddition that required surgery). But now I take only on demand which is just a couple of times a year and I doubt it really matters what I take. I have been very cautious about taking anything that requires long term meds. We always find out later about the "unknown" or "suddenly revealed" side effects. When arthritis started to become a problem years ago I rejoiced when Vioxx and celebrex were discoveredand I took every day until the heart issues side effects became widely known. Sidenote, I still take advil for occasional pain, so how safe is that. I took lipitor to lower cholesterol for a while but decided that was too risky to take that long term. And I wonder if just lowering the number is important? Lots of people take medication for high blood pressure. I know people who take more than one daily. I wonder how smart that is. On my wife's Mothers side, all the women live to be about 100 and they all have high blood pressure. Her Grandmother loved the fat on meats like prok chops and ate it all the time. So does lowering high blood pressure matter for everyone or only certain people? ( and do they rig the clinical trials to especially accept people like the females in my wife's family who can live to a ripe old age even with the condition? Charlie, I wonder the same things. I have familial high blood pressure and high cholesterol- my body produces too much. I asked my doctor if high cholesterol was really an issue for some people and he said that "they" just don't know what is normal for some and not others. I agreed to go on crestor (the supposed best of them) if he could prove that I needed it. I had an ultrasound on my neck. It was fine. But, at the same time, my dad's brain literally blew up. I take crestor now. I had heart issues with naprosyn. I was taking 1000 mg a day. (prescribed) It gave me bad heart palpitations. I have tried every nsaid since and have not found one that I am comfortable taking. I don't think the medical community knows everything. Again high blood pressure can be from so many things. There are various safe ways to lower it though. What works best will depend on the cause. If not sure then a sterol source such as jiaogulan (Gynostemma) will work. Sterols relax the blood vessels lowering the blood pressure. Sterols also bind cholesterol in the gut preventing absorption and reabsorption thus lowering cholesterol. If you make the tea a little stronger this will also hep with lowering cholesterol in an different way. The tea can be rather bitter if made strong. The bitterness stimulates the bitter receptors of the tongue. This in turn stimulates the vagus nerve, which increases stomach acid, bile and pancreatic enzymes. This is why there are bitter herbs called "digestive bitters" used to help with things like indigestion and acid reflux. The vagus nerve stimulation also improves liver function, which can help with hormone balance and cholesterol issues. I have never seen any real evidence that high cholesterol is hereditary. If a person has a truly hereditary condition then they have it from birth, not decades down the line. The main two reasons for chronic high cholesterol are liver dysfunction and/or thyroid dysfunction. The liver is the main cholesterol regulator for the body. When cholesterol levels are low the liver synthesizes cholesterol since it is essential for so many things in the body. When cholesterol levels are high the liver should break down the excess cholesterol if everything is working properly. The thyroid's role is through the metabolism of fats including cholesterol. Women are more prone to hypothyroidism due to their higher estrogen levels, which suppresses the thyroid and lab tests FREQUENTLY miss cases of hypothyroidism for several reasons. Low basal body temperature combined with other symptoms of hypothyroidism (low energy, weight gain in some cases, cold intolerance, hair falling out all over, dry hair and skin, etc.) can detect cases of hypothyroidism missed by lab tests. A major problem with the statin drugs like Crestor is that they can not only cause heart failure, but they can also cause liver damage that ironically can lead to increased cholesterol levels. The heart failure is due to a condition known as rhabdomyolosis, which is the result of a breakdown of muscle tissue. This is the result of the statin drugs inhibiting adenosine triphosphate (ATP) formation to the muscles. ATP is the "fuel" for the cells and allows them to work properly. The fact that the heart is also a muscle means that it is also prone to rhabdomyolosis and thus heart failure. The supplement CoQ10 is often taken with statin drugs since CoQ10 increases ATP levels. As for Crestor supposedly being the best I recommend looking up the Jupiter Study in relationship to Crestor and the fraud behind it. The drug company that produces Crestor got caught in a big scandal for manipulating their test results to make their drug appear more effective than it really was. Another good choice in your case I would recommend is the herb coleus forskohlii. Forskohlii is a very mild cardiac glycoside for one. In short this means it will lower the blood pressure and slow and strengthen the heart contractions while improving blood flow to the heart reducing palpitations. It also increases cAMP to help with psoriasis. Taking it with nettle leaf will prolong the effects. As for cholesterol levels they are actually unimportant when assessing the risk of heart attack and stroke. In fact, 50% of people who die fro heart attacks have low to normal levels of cholesterol and low cholesterol is considered one of the greatest risk factors to develop a heart attack. I know it sounds contradictory to what we have been told by the drug companies to sell their drugs, but there is very sound science behind all of this. First of all arterial plaque is not the result of high cholesterol. Arterial plaque is the result of arterial inflammation. Cholesterol is a healing agent for the body. Even if you slice your hand cholesterol will flood the area to help act as a patch to the injury and to aid in healing. In the case of arterial inflammation the same thing happens. If the inflammation is chronic then the cholesterol keeps coming in and depositing leading the plaque formation, which later calcifies. This is why people can still develop arterial plaque with normal to low cholesterol levels and why bypasses tend to fail within 3-5 years. Low cholesterol increases the risk of heart attack and stroke because cholesterol is essential for the formation of prostaglandins. And remember what I said about prostaglandins earlier? Some of the prostaglandins dilate the blood vessels to increase oxygen and nutrients to injured areas to aid in healing. Therefore, low cholesterol decreases prostaglandin levels thereby decreasing blood flow to the heart and brain increasing the risk of heart attack and stroke. As for why the NSAID is causing your heart palpitation this is easy to explain. Again this goes back to the prostaglandin inhibition decreasing blood flow. I have a write up I will post at the end that will explain this a little more in detail. In short though the lack of proper blood flow to the heart decreases tissue oxygenation to the heart. This leads to the formation of ectopic pacemakers that act like the nodes that control the heart rhythm. Since the ectopic pacemakers are also firing off like nodes they cause the heart to beat out of rhythm. Here is my write up: medcapsules.com/forum/showthread.php?tid=3380
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Post by vegasjames on Apr 16, 2016 17:21:27 GMT -5
I was hoping vegasjames might find this. I am wondering what he thinks of the curcumin. I'm glad that I switched. I feel a lot better on the whole. And, I eliminated 2 meds. Curcumin is great and its benefits go beyond inflammation control such as inhibiting cancer through a variety of mechanisms. It is poorly absorbed though, which is why they probably mixed it with lecithin or some surfactant to increase the bioavailability. Generally in nature when something is hard to absorb there tends to be a very good reason for it. In this case I feel the reason is that curcumin is a derivative of turmeric, which is extremely high in oxalic acid. Luckily most dietary oxalic acid is not absorbed very well since it trends to bind to other things like calcium blocking the absorption of the oxalic acid by creating insoluble compounds. Still you don't want to absorb much oxalic acid since it can wreak havoc on the body so I think nature made its own way to reduce absorption. The extracted curcumin, which is only one of the active components in turmeric, will not be a problem since the oxalic acid should be mostly to completely removed in the extraction process. Still there are more effective anti-inflammatories. Personally I like licorice root and yucca root (Yucca schidegra), which are both strong steroidal anti-inflammatories. And licorice root tastes great. It is 50 times sweeter than sugar. It does not taste like black licorice candy as some people believe. Black licorice is most often flavored with star anise. That being said I also want to point out that there are a lot of claims out there about how licorice root can cause high blood pressure. This is somewhat misleading since this requires a daily intake of at least 50 grams (that is an entire bottle of capsules) daily for at least 6 months to have this effect. And this can be countered simply by increasing potassium intake. Coffee or NSAIDs will have a much faster and more dramatic effect on blood pressure. Licorice root should not be taken though if on steroids though such as Prednisone without supervision since licorice root prolongs the effects of steroids. Yucca root should not be taken in cases of bleeding ulcers as the saponin content hemolyzes red blood cells, which can lead to more pain.
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Post by vegasjames on Apr 16, 2016 17:31:00 GMT -5
Good replies, even yours Scott. rockjunquie , my wife picked up some tumeric/curcumin the other day. After she got it I did a little reading on it. It appears that it needs to be used along with Piperine so that the body can use it in the extremities for joint/muscle aches. Does what you're using have Piperine in it...I'm thinking so since you mention that it's "bio available". Thanks for the good report on Curcumin!!! chassroc , it's good that you can take the meds on demand now, I may have to go that route. My problem was reflux at night...to the point I began to worry about esophageal erosion/cancer (I was probably over reacting, but...). Yes, long term use of a medicine can hurt you as much as it helps. But in some situations/conditions there is no alternative and "we do what we gotta do". I've been on generic Lipitor (atorvastatin) for the last year and a half due to LBBB. It has kept my cholesterol numbers down nicely, which I need to keep down. But, I'm thinking that some strange "pains" that I've been getting in my arms and legs are due to the statin...hurts at times enough to wake me in the middle of the night. As for people living to be old while having high blood pressure (and other "ailments") I had an old friend that smoked all of his life...he lived to be in his early 90's....I guess those cigarettes killed him. Naturally, there was a bit of sarcasm in that as it's a fact that cigarette smoking lowers most people's life expectancy and/or quality. Some people smoke all of their lives, live to be old, and never appear to be adversely affected by the smoke BUT they are the exceptions...there are exceptions to most anything so I'm sure there's people who are not seriously affected by high blood pressure. I agree that the medical profession doesn't know everything. Today, it is a good chance that if you or your family isn't proactive in pursuing truth in a loved ones diagnosis and treatment then you or your family may sadly find yourself soon making an appointment with a funeral director. Piperine is a black pepper alkaloid extract patented by Sabinsa Corporation. It is added to various formulas to enhance the absorption of compounds. The pain in your arms and legs could be the start of rhabdomyolosis. I posted more information on this in an earlier post. You need to let you r doctor know about this since this can be a very serious conditions and as i pointed out the heart can be affected the same way leading to heart failure. Supplementing with CoQ10 (at least 200mg daily to be effective) will help as it increases ATP to the muscles. It generally has an oil source mixed with it such as vitamin E to enhance absorption. I also like magnesium malate to increase ATP. Both magnesium and the malic acid it is combined with increase ATP levels. The magnesium also lowers blood pressure by acting as a natural calcium channel blocker and improves blood flow to the heart.
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Post by rockjunquie on Apr 16, 2016 17:45:51 GMT -5
vegasjames Thank you very much for taking the time to write all of this and share your wealth of knowledge. I have to fully digest this and I think I will have a couple questions afterward. I hope you won't mind. I'll just pm you.
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Post by vegasjames on Apr 16, 2016 17:57:26 GMT -5
vegasjames Thank you very much for taking the time to write all of this and share your wealth of knowledge. I have to fully digest this and I think I will have a couple questions afterward. I hope you won't mind. I'll just pm you. No problem. This is what I do most of the day most days anyway. I answer people's health questions and argue with people on YouTube health videos that do not understand basic chemistry or human physiology. Sometimes I get really busy and it can take time for me to respond, but I will.
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Post by MrP on Apr 16, 2016 19:28:59 GMT -5
vegasjames Thank you very much for taking the time to write all of this and share your wealth of knowledge. I have to fully digest this and I think I will have a couple questions afterward. I hope you won't mind. I'll just pm you. No problem. This is what I do most of the day most days anyway. I answer people's health questions and argue with people on YouTube health videos that do not understand basic chemistry or human physiology. Sometimes I get really busy and it can take time for me to respond, but I will. rockjunquie vegasjames If the questions and answers are not too personal could you keep it going on this thread? Some of us do a lot more reading then posting. I find most people on this board have great info on all topics, even those not rock related. Thank You......................MrP
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Post by rockjunquie on Apr 16, 2016 19:33:28 GMT -5
No problem. This is what I do most of the day most days anyway. I answer people's health questions and argue with people on YouTube health videos that do not understand basic chemistry or human physiology. Sometimes I get really busy and it can take time for me to respond, but I will. rockjunquie vegasjames If the questions and answers are not too personal could you keep it going on this thread? Some of us do a lot more reading then posting. I find most people on this board have great info on all topics, even those not rock related. Thank You......................MrP If I find that my questions are not too personal, I can ask here. I have done some research- enough to know that what James is saying is not BS. I really value his input.
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